Pathology of coronary microembolisation and no reflow
نویسندگان
چکیده
منابع مشابه
Spontaneous and interventional coronary microembolisation.
SPONTANEOUS CORONARY MICROEMBOLISATION The development of coronary atherosclerosis can be subdivided into five stages according to the American Heart Association. Atheroma and fibroatheroma, stage IV and V lesions, are characterised by lipid core formation. When the ratio of the lipid core to total plaque size increases and the fibrous cap thickness decreases < 60 μm , the risk of rupture is en...
متن کاملIncidence and treatment of 'no-reflow' after percutaneous coronary intervention.
BACKGROUND Profound reduction in antegrade epicardial coronary flow with concomitant ischemia is seen occasionally during percutaneous coronary intervention despite the absence of evident vessel dissection, obstruction, or distal vessel embolic cutoff. In a prior small series of cases, this "no-reflow" phenomenon appeared to be promptly reversed by the intra-coronary administration of verapamil...
متن کاملNo - Reflow
A. DEFINITION. The no-reflow phenomenon was originally observed in experimental models of acute myocardial infarction (MI) and was described as a failure to restore normal myocardial blood flow despite removal of the coronary obstruction. Since that time, no-reflow has been shown to complicate thrombolytic therapy and percutaneous revascularization with PTCA and other devices. Defined angiograp...
متن کاملDemonstration of the "no-reflow" phenomenon by digital coronary arteriography.
6. Kennedy JW, Ritchie JL, Davis KB, Fritz JK. Western Washington rondomized trio1 of intracoronory streptokinase in acute myocordiol infarction. N Engl J Med 1983;309:1477-1482. 7. Schuler G. Schwarz F, Hofmann M, Mehmel H, Manthey J, Maurer W, Rauch B, Herrmann HJ, Kubler W. Thrombolysis in acute myocordiol injarction using intracoronary streptokinose: assessment by thallium-201 scintigraphy....
متن کاملCapillary pericytes mediate coronary no-reflow after myocardial ischaemia
After cardiac ischaemia, a prolonged decrease of coronary microvascular perfusion often occurs even after flow is restored in an upstream artery. This 'no-reflow' phenomenon worsens patient prognosis. In the brain, after stroke, a similar post-ischaemic 'no-reflow' has been attributed to capillary constriction by contractile pericytes. We now show that occlusion of a rat coronary artery, follow...
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ژورنال
عنوان ژورنال: Heart
سال: 2003
ISSN: 0007-0769
DOI: 10.1136/heart.89.9.983